Best Weed Strains For Pain And Depression

While, at the time of this writing, it remains illegal for doctors to prescribe medical marijuana in all but a handful of states, many people with chronic pain and depression believe that cannabis has been their saving grace. While more research is needed before we can conclusively state that this is true, anecdotal evidence from thousands of patients supports the theory that weed can help treat pain and depression. If you’re curious about whether medicinal marijuana could be right for you—and if so which strains you should use—read on!

Granddaddy Purple

Granddaddy Purple is a popular indica strain that’s been around for years. It’s a cross between Big Bud and Purple Urkle, and it has a sweet berry flavor that makes it easy to smoke. Granddaddy Purple is great if you’re looking for pain relief, stress relief, or anxiety relief—and it’s one of the best choices for beginners who want something that won’t knock them out too hard at first.


ACDC is a hybrid strain that is popular in Canada. ACDC has a THC content of 15-20% and CBD content of 0.1%. When smoked, ACDC will give you an uplifting effect with some body relaxation. This strain is known to be effective for relief from pain, stress, depression and anxiety.

ACDC may be ideal if you have any one or more of the following symptoms:

  • Pain
  • Stress and anxiety


Harlequin, the strain that gave you that blissful euphoria and pain-free feeling, is the result of a cross between Northern Lights and White Widow. It’s a Sativa dominant hybrid that was bred by Nirvana Seeds in 1994.

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Harlequin is known to be one of the best strains for depression and anxiety relief and appetite stimulation. This strain is also great for beginners because it’s easier to smoke than most other strains on this list, making it ideal for those who aren’t yet accustomed to smoking or vaporizing cannabis flower products.


Cannatonic is a hybrid strain that is 60% sativa and 40% indica. It’s a cross between Skunk #1 and G13 Haze, both of which are known for their high CBD content. Cannatonic has been bred to increase the level of CBD in its genetics, making it one of the best strains for depression and pain due to its great therapeutic side effects.

Cannatonic can be used in several ways depending on your needs:

  • Indica: Use this if you’re looking for relaxation and sedation without too much euphoria or anxiety.
  • Sativa: If you need motivation or energy but want your mind clear of any foggy thinking, this will help with that!

Northern Lights

Northern Lights is an indica-dominant hybrid that offers a balanced high. It has been a favorite cannabis strain since the 1980s and one of the most popular strains in the world.

Northern Lights is known for its relaxing effects that can help ease pain, stress and anxiety without making you feel too sedated. The THC content in this strain ranges from 15 to 20 percent. The CBD content hovers around 0.3 percent (with higher amounts found in some plants).

For patients new to cannabis or those who are looking for a milder high with fewer cognitive side effects, Northern Lights is a good choice because it delivers relief without leaving you feeling overly stoned or groggy afterward.

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Blue Dream

Blue Dream is a hybrid strain of cannabis sativa that has won over the hearts of many with its sweet and fruity taste. It’s a cross between Blueberry and Haze, two classic strains that have been around for decades.

Blue Dream has a high THC content, meaning it will give you a strong high if you’re looking to get stoned out of your mind. But this isn’t just some reckless time-waster—it’s also very calming, helping those who suffer from depression or anxiety to find calmness in their day-to-day life.

Many medicinal marijuana users report that these strains work well for them.

Many medicinal marijuana users report that these strains work well for them. However, you should always use medical marijuana as a last resort. This is because it’s important to first try all other options available to you, such as exercise and meditation. If those don’t get the job done, then you can move on to using medical marijuana as a second resort. Finally, if your pains or depression are still not relieved by those methods (or even after trying them), then it might be time to give up and use medical marijuana as your final recourse.

If you’ve been thinking about incorporating cannabis into your health routine, ask your doctor or budtender for more information on these strains. It can be hard to find the right strain for you when there are so many options out there. But by choosing one of the above strains and starting small, you might just find relief for aching joints or depression—and have some fun in the process!

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